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ea0056p784 | Pituitary - Basic | ECE2018

CGH array analysis of pituitary tumors revealed a highly-disrupted genome

Lasolle Helene , Elsensohn Mad-Helenie , Alix Eudeline , Bonnefille Clement , Michel Jessica , Bardel Claire , Roy Pascal , Sanlaville Damien , Raverot Gerald

Introduction: Genetic of pituitary tumors (PT) is incompletely understood. The aim of this study was to search for somatic copy number variations (CNV) in pituitary tumors and evaluate their prognostic impact on tumor recurrence.Methods: CGH array analysis (Agilent SurePrint G3 Human CGH+SNP Microarray 4×180 K) was performed on 196 fresh-frozen PT (67 gonadotroph, 31 corticotroph, 38 prolactinomas, 60 somatotroph). PT were classified according to th...
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Published by BioScientifica

Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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